Skip to main content
. 2021 Jul 20;41(7):BSR20210609. doi: 10.1042/BSR20210609

Figure 4. The effect of Tgr5 on the biomarker and mRNA in Tgr5- mice.

Figure 4

(A) IL-6. (B) TNF-α. (C) VEGF. (D) Cortisol. (E) INF-γ. (F) Heat map and histogram of mRNA expression in the skin. Data are expressed as the means ± standard deviation. One-way ANOVA followed by Tukey’s multiple tests has been used; n = 10 per group; IL-6, interleukin-6; INF-γ, interferon-γ; JAK1, Janus kinase1; KO, knockout; MMP-1, matrix metalloproteinase-1; STAT3, signal transduction and activator of transcription; Tgr5, G-protein-coupled bile acid receptor-5; TNF-α, tumor necrosis factor-α; * P<0.05, ** P<0.01. VEGF, vascular endothelial growth factor; WT, wild-type.