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Miz1 represses Ace2 transcription in mouse lung epithelial cells. (A) Ace2 mRNA expression in MLE-12/Miz1(WT) and MLE-12/Miz1(δPOZ) cells as analyzed by RT-qPCR. (B, C) Ace2 mRNA (B) and protein expression (C) in the control KP cells (Ctrl), Miz1 KO KP cells (Miz1−/−) or Miz1 KO KP cells expressing exogenous Miz1 (Miz1+). Data are presented as means ± sem from three to four independent experiments. *p < 0.05, **p < 0.01, ***p < 0.001 and ****p < 0.0001.
