Figure 5.

Knockdown of MIZ1 also increases ACE2 expression in human lung epithelial cells. (A, C, E, F) ACE2 mRNA levels in the parental 2122, A549, H23, or BEAS-2B cells, or their corresponding cells expressing control shRNA (shCtrl) or shRNA(s) against Miz1 (shMiz1). (B, D, G) Protein expression of ACE2, Vinculin, and Miz1 in 2122, A549, or BEAS-2B cells stably expressing shCtrl or shRNA(s) against Miz1. Data are presented as means ± sem from three independent experiments. *p < 0.05, **p < 0.01 and ***p < 0.001.