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Phenotypic co-receptor tropisms of HIV-1 non-B subtypes isolated in Tanzania. Relative infectivity of lentivirus reporters pseudotyped with control envelopes, NL43 and JRFL (A) and a panel of patient-derived envelope clones (B) are shown. Target cells were U87.CD4 cells expressing either R5 or X4 co-receptor. Data represent the mean of triplicate assays. The background level of luminescence signal was 200 (2.3log) RLU and is represented by the dotted lines.
