Figure 3.

Applicator for applying Candlelit‐DMNs. a) The disposable pillar array and the Candlelit‐DMN mounted perforated substrate are set on the shooting device. Activating the spring gear in the shooting device causes each plastic pillar to hit each Candlelit‐DMN, resulting in each Candlelit‐DMN being stably inserted into the human skin in vivo. b) The perforated substrate on which Candlelit‐DMNs are mounted is observed with a microscope before and after activating the shooting device of the applicator. White bar: 1 mm.