Table 1.
A list of 33 defined EWS–FLI1 downstream target protein abundance reduced by OTUD7A depletion in A673 cells
| Gene | log2 ‐Tet vs +Tet fold change |
|---|---|
| SRSF protein kinase 1 (SRPK1) | −0.5 |
| cell division cycle‐associated protein 3 (CDCA3) | −0.52 |
| cell division cycle protein 20 homolog (CDC20) | −0.52 |
| thymidylate synthase (TYMS) | −0.52 |
| paternally‐expressed gene 3 protein (PEG3) | −0.53 |
| transcription factor E2‐alpha (TCF3) | −0.55 |
| adrenodoxin, mitochondrial (FDX1) | −0.56 |
| CYFIP‐related Rac1 interactor A (FAM49A) | −0.56 |
| Friend leukemia integration 1 transcription factor (FLI1) | −0.57 |
| ATPase family AAA domain‐containing protein 2 (ATAD2) | −0.57 |
| proline/serine‐rich coiled‐coil protein 1 (PSRC1) | −0.59 |
| pre‐B‐cell leukemia transcription factor 1 (PBX1) | −0.6 |
| poly(A) polymerase alpha (PAPOLA) | −0.61 |
| pro‐neuregulin‐1, membrane‐bound isoform (NRG1) | −0.62 |
| homeobox protein Nkx‐2.2 (NKX2.2) | −0.67 |
| ephrin type‐B receptor 3 (EPHB3) | −0.68 |
| propionyl‐CoA carboxylase alpha chain, mitochondrial (PCCA) | −0.73 |
| sal‐like protein 2 (SALL2) | −0.7 |
| noelin (OLFM1) | −0.76 |
| death‐associated protein kinase 2 (DAPK2) | −0.7 |
| DNA endonuclease RBBP8 (RBBP8) | −0.79 |
| frizzled‐1 (FZD1) | −0.8 |
| centromere protein M (CENPM) | −0.81 |
| regulator of chromosome condensation (RCC1) | −0.84 |
| DEP domain‐containing protein 1A (DEPDC1) | −0.86 |
| LIM domain‐binding protein 2 (LDB2) | −0.88 |
| PAX‐interacting protein 1 (PAXIP1) | −1.08 |
| musculin (MSC) | −1.09 |
| neuropeptide Y receptor type 1 (NPY1R) | −1.1 |
| ephrin‐B1 (EFNB1) | −1.1 |
| homeodomain‐interacting protein kinase 1 (HIPK1) | −1.11 |
| influenza virus NS1A‐binding protein (IVNS1ABP) | −1.24 |
| growth arrest‐specific protein 1 (GAS1) | −1.56 |