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. 2021 May 17;12(7):1121–1141. doi: 10.1039/d1md00045d

Fig. 7. Drugs with established PKM2 inhibitory activity. Tanshinone IIA (12), cyclosporin inhibitor (13), pantoprazole (14), TLN-232 (15), 3,3,5-triiodothyronine (16), metformin (17), and suramin (18) show PKM2 inhibitory properties. The red portion in the molecule signifies the part with PAINS propensity.

Fig. 7