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. 2021 Jul 7;9:707970. doi: 10.3389/fcell.2021.707970

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Copyright © 2021 Dong, Liu, Deng, Shao, Tian, Chen, Huang, Lin, Chen and Shen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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C1GALT1 promotes LUAD tumor growth in vivo. (A) Representative images of excised tumors from nude mice injected with C1GALT1-overexpressing cells. (B,C) Analysis of tumor volume (B) and weight (C) after C1GALT1 overexpression. (D) Representative images of excised tumors from nude mice injected with C1GALT1-knockdown cells. (E,F) Analysis of tumor volume (E) and weight (F) after C1GALT1 knockdown. n = 3 mice per group. Mock, cells transfected with empty plasmid; OV, cells transfected with C1GALT1 overexpression plasmid; shNC, cells infected with negative control shRNA; shRNAs, cells infected with C1GALT1 shRNA. Data are expressed as mean ± SD. *p < 0.05.