Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Jul 7;9:707970. doi: 10.3389/fcell.2021.707970

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Dong, Liu, Deng, Shao, Tian, Chen, Huang, Lin, Chen and Shen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

RAC1 serves as a downstream effector of C1GALT1 in LUAD. (A,B) Analysis of RAC1 expression in C1GALT1-overexpressing cells after transfection with RAC1 siRNA by qPCR (A) and Western blot (B). (C–E) The proliferation, migration, and invasion of cells co-transfected with C1GALT1 overexpression plasmid and RAC1 siRNA were determined by CCK-8 assay (C), Transwell migration assay (D), and Matrigel invasion assay (E). (F) Representative images of excised tumors from nude mice (n = 3 per group). (G,H) Tumor volume (G) and tumor weight (H) were measured. siNC, cells transfected with non-silencing siRNA; siRNA, cells transfected with RAC1 siRNA. Data are expressed as mean ± SD. *p < 0.05.