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. 2021 Jul 7;12:648868. doi: 10.3389/fmicb.2021.648868

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Copyright © 2021 Malhotra, Kaur and Phale.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Fate of formaldehyde generated during carbamate degradation. Non-enzymatic reactions are represented by dashed lines whereas enzymatic reactions are represented by solid lines. Enzymes involved are: FADH, Formaldehyde dehydrogenase; FAE, Formaldehyde activating enzyme; FOLD, bifunctional Methylene-H4-Folate (CH₂ = H₄F) dehydrogenase-methylenetetrahydrofolate cyclohydrolase; MTDA, Methylenetetrahydrofolate (CH₂ = H₄F) dehydrogenase; MTDB, NAD(P)-dependent Methylene-tetrahydromethanopterin (CH₂ = H₄MPT) dehydrogenase; and FDH, Formate dehydrogenase.