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Summary of alterations seen in GC cell types at late stages of GC reaction. These alterations might play a causal role in GC shutdown by influencing the fate decisions of GC B cells shown in Figure 1 or act as a contributing factor to GC shutdown. GC, Germinal centre; FDCs, Follicular dendritic cells; Tfr, T follicular regulatory cells; Tfh, T follicular helper cells, B, GC B cells; TCR, T cell receptor; BCR, B cell receptor; PC, Plasma cell; Bm , Memory B cell; Ag, Antigen.
