Table 1.
Hemoglobin disorders in Filipino newborns—California vs. Philippines (adapted from Reference [11]).
| Hemoglobin Disorders |
a Cases in Filipino Newborns Born in California 7 July 2005–6 July 2011 |
a Prevalence in Filipino Newborns Born in California 7 July 2005–6 July 2011 |
b Estimated Annual Cases of Filipino Newborns Born in Philippines |
|---|---|---|---|
| Hb H Disease | 93 | 1:1195 | 1860 |
| α Thalassemia Major | 5 | 1:22,225 | 100 |
| Homozygous E/E | 3 | 1:37,042 | 60 |
| Hb H/Constant Spring Disease | 2 | 1:55,564 | 40 |
| Hb SC Disease | 2 | 1:55,564 | 40 |
| Hb E/β+ Thalassemia | 1 | 1:111,127 | 20 |
| β Thalassemia major | 1 | 1:111,127 | 20 |
| Hb Variant/β+ Thalassemia | 1 | 1:111,127 | 20 |
| Hb SS Disease | 1 | 1:111,127 | 20 |
| Totals | 109 | 1:1020 | 2240 |
a Detected as part of California newborn screening program (n = 111,127). Parents included: Filipino-Filipino (61,088); Filipino-White (18,546); Filipino-Hispanic (8507); Filipino-Hispanic-White (3849); Filipino-Other (19,127); b assuming 100% coverage of 2 million annual births; overall prevalence (109 cases in 111,127 births).