Table 2.
List of the five biomarkers of foie gras liver weight identified with the metabolite method.
| Metabolites | VIP-valuesε | BH p-valuesζ | R2 |
|---|---|---|---|
| Lactate | 4.11 | <0.001 | 0.65 |
| Glucose | 2.87 | <0.001 | 0.51 |
| Threonine | 1.72 | <0.001 | 0.62 |
| Alanine | 1.55 | <0.001 | 0.35 |
| Taurine | 1.29 | <0.001 | 0.26 |
ε
The PLS model to describe the liver weight with metabolite data was plotted. The first latent variable enabled to separate the fatty livers in function of the liver weight. The metabolites with VIP superior to 1 were selected. The VIP of the metabolite was indicated.
ζ
For each biomarker, the effect of their relative concentration on the liver weight was tested by a linear model with R software, and p-values were corrected with the Benjamini-Hochberg procedure and named BH p-values.