Table 2.
Relationship between LND and demographics/clinicopathologic characteristics.
| Demographics/clinicopathologic characteristics | LND (n = 528) | P-value | |||
|---|---|---|---|---|---|
| ≤9.3% (n = 328) | >9.3% (n = 200) | ||||
| No. of patients | % | No. of patients | % | ||
| Age at diagnosis (year) | 35 | 17.5 | 0.003 | ||
| <50 | 61 | 18.6 | 87 | 43.5 | |
| 50–69 | 184 | 56.1 | 78 | 39.0 | |
| ≥70 | 83 | 25.3 | |||
| Marital status | 0.6 | ||||
| Married | 189 | 57.6 | 117 | 58.5 | |
| divorced | 35 | 10.7 | 29 | 14.5 | |
| widowed | 25 | 7.6 | 14 | 7.0 | |
| single | 68 | 20.7 | 33 | 16.5 | |
| unknown | 11 | 3.4 | 7 | 3.5 | |
| Grade | 0.000 | ||||
| G1 | 61 | 18.6 | 12 | 6.0 | |
| G2 | 182 | 55.5 | 101 | 50.5 | |
| G3 | 67 | 20.4 | 75 | 37.5 | |
| G4 | 2 | 0.6 | 5 | 2.5 | |
| Unknown | 16 | 4.9 | 7 | 3.5 | |
| T-stage | 0.001 | ||||
| T1 | 93 | 28.4 | 45 | 22.5 | |
| T2 | 148 | 45.1 | 71 | 35.5 | |
| T3 + T4 | 87 | 26.5 | 84 | 42.0 | |
| N-stage | 0.000 | ||||
| N0 | 238 | 72.6 | 0 | 0.0 | |
| N1 | 52 | 15.9 | 63 | 31.5 | |
| N2 | 27 | 8.2 | 88 | 44.0 | |
| N3 | 11 | 11.3 | 49 | 24.5 | |
| M-stage | 0.002 | ||||
| M0 | 323 | 98.5 | 187 | 93.5 | |
| M1 | 5 | 1.5 | 13 | 6.5 | |
| Histological type | 0.007 | ||||
| SCC | 300 | 91.5 | 191 | 95.5 | |
| PC | 13 | 4.0 | 2 | 1.0 | |
| LC | 15 | 4.5 | 3 | 1.5 | |
| BCC | 0 | 0.0 | 1 | 0.5 | |
| TCC | 0 | 0.0 | 3 | 1.5 | |
| ELN | 0.000 | ||||
| ≤13 | 109 | 33.2 | 112 | 56.0 | |
| >13 | 219 | 66.8 | 88 | 44.0 | |
| Tumor size | 0.012 | ||||
| ≤3.5 cm | 191 | 58.2 | 94 | 47.0 | |
| >3.5 cm | 137 | 41.8 | 106 | 53.0 | |
| Surgery of primary site | 0.012 | ||||
| LTE | 38 | 11.6 | 22 | 11.0 | |
| SS | 276 | 84.1 | 156 | 78.0 | |
| RS | 14 | 4.3 | 22 | 11.0 | |
SCC, Squamous cell carcinoma; PC, Papillary carcinoma; LC, Lymphoepithelial carcinoma; BCC, Basal cell carcinoma; TCC, Transitional cell carcinoma; LTE, Local tumor excision; SS, Simple/partial surgical removal of primary site; RS, Radical surgery; ELN, Examined lymph node; LND, Lymph node density.