Table 3.
Correlations among depression, anxiety, exposure to SEA, and immune cell infiltrates.
| Variables | CD68 Macrophages | CD3 T-Cells | CD19 B-Cells |
|---|---|---|---|
| PHQ-8 total score (depression symptoms) | 0.224 | 0.466 * | 0.581 |
| Depression symptoms (current) | 20.000 | 33.500 | 33.000 |
| Hx. of Depression | 32.000 | 49.000 | 44.000 |
| GAD-7 total score (anxiety symptoms) | 0.098 | 0.013 | 0.189 |
| Adverse Childhood Events (ACE, total score) | 0.805 | 0.886 | 0.457 |
| Trauma History Questionnaire (THQ, total score) | −0.054 | 0.015 | 0.173 |
| THQ/Crime-related events (total score) | 0.163 | 0.067 | 0.216 |
| THQ/Crime-related events (average age) | |||
| THQ/General disasters and trauma (total score) | - | 0.166 | 0.109 |
| THQ/General disasters and trauma (average age) | |||
| THQ/Physical and Sexual experiences (total score) | 0.067 | 0.288 | −0.034 |
| THQ/Physical and Sexual experiences (average age) | |||
| Comorbid ACE + Hx. of Depression | 30.000 | 32.500 | 26.000 |
| Comorbid ACE + Anxiety | 20.000 | 23.500 | 16.000 |
| Comorbid THQ/Crime + Hx. of Depression | 24.000 | 28.000 | 34.000 |
| Comorbid THQ/Crime + Anxiety | 18.000 | 22.000 | 10.000 * |
| Comorbid THQ/Disaster and trauma + Hx. of Depression | 32.000 | 49.500 | 34.000 |
| Comorbid THQ/Disaster and trauma + Anxiety | 20.000 | 23.500 | 16.000 |
| Comorbid THQ/Physical and sexual abuse + Hx. of Depression | 32.000 | 49.500 | 34.000 |
| Comorbid THQ/Physical and sexual abuse + Anxiety | 12.000 | 8.000 * | 20.000 |
* p < 0.05.