Table 3.

Summary of the CD4+ T-cell population lethal and nonlethal (protective) cytokine signatures. Comparisons between lethal (Karp IP) and nonlethal (Karp ID, Woods IP, Woods ID) challenge models were performed in an intra- and interstrain fashion. Lethal signatures are designated by an asterisk (*) and nonlethal (protective signatures) are indicated by a hashtag (#), each indicating a significant increase (p < 0.05) in the associated population of cytokine-producing cells.

Karp IP vs Karp ID	IFN	IL2	TNF	IFN-IL2	IFN-TNF	IL2-TNF	IL2-TNF-IFN
10d vs 14d				*
10d vs 21d				*			*
14d vs 21d							*
Karp IP vs Woods IP	IFN	IL2	TNF	IFN-IL2	IFN-TNF	IL2-TNF	IL2-TNF-IFN
10d vs 10d				*			*
10d vs 21d		#		*		#	*
14d vs 21d		#		*		#	*
Karp IP vs Woods ID	IFN	IL2	TNF	IFN-IL2	IFN-TNF	IL2-TNF	IL2-TNF-IFN
10d vs 10d				*			*
10d vs 21d		#		*		#	*
14d vs 21d		#		*		#	*