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. 2021 Jun 8;9(2):28. doi: 10.3390/proteomes9020028

Figure 1.

Figure 1

Differentiation among the four fiber types. (a) Principal component analysis (PCA) of fiber types (n = 56). Significant separation of type IIb (purple) and type IIx fibers (green) can be observed in principle component (PC2), while type I (blue) and type IIa fibers (red) formed a combined, but significantly separated, cluster from type IIx and type IIb fibers in PC2 with moderate segregation into type I and type IIa fibers. (b) PCA loadings, visualizing the proteins separating the four groups. The four fiber type characteristic myosin heavy chain (MYH) isoforms are indicated in red and were identified as major separators.