Table 7.
Classification of fiber types according to the traditional classification based on ATPase staining, the oxidative phosphorylation capacity, the immunohistochemical classification based on myosin heavy chain (MYH) isoforms, and the classification based on the proteomic data.
Fiber Type | Traditional Classification (Based on ATPase Staining) | Oxidative Phosphorylation Capacity | Immunohistochemical Classification via MYH Isoform |
Proteomic Classification |
---|---|---|---|---|
Type I | Slow | Very high | MYH7 | Highly oxidative |
Type IIa | Fast | High | MYH2 | Highly oxidative |
Type IIb | Fast | Very low | MYH4 | Highly glycolytic |
Type IIx | Fast | Low | MYH1 | Oxidative and glycolytic |