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. 2021 Jul 16;9(3):51. doi: 10.3390/medsci9030051

Table 1.

Postburn interventions aimed at reducing thermally induced apoptosis.

Intervention Effect Burn Model Timing Reference
Human amniotic MSC Decreased TUNEL staining mouse postburn Li et al. [69]
Inhibitor of c-jun Decreased cell death mouse potburn Giles et al. [70]
Rapamycin Decreased TUNEL staining rat postburn Xiao et al. [71]
Methylene Blue Reduced necrosis rat postburn Rosique et al. [67]
Granzyme B inhibitor Improved healing mouse postburn Shen et al. [64]
Hsp90α fragment F-5 Reduced caspase 3 staining pig postburn Bhatia et al. [72]
Platelet Rich Plasma Reduced TUNEL rabbits postburn Uraloğlu et al. [73]
Astaxanthin Reduced TUNEL staining, reduced cytochrome C and caspase 9 postburn Fang et al. [68]
Melatonin Reduced caspase 3 staining rat postburn Zhang et al. [74]
p38MAPK inhibition Reduced TUNEL rat postburn Ipaktchi et al. [75]

MSC-mesenchymal stem cells, TUNEL TdT-mediated dUTP biotin nick end-labelling.