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Changes in the RyR2 interactome based on phosphorylation status of S2814. As representatives of other putative interactors, Aifm1 and Idh3b have decreased binding to RyR2 S2814D mimicking phosphorylated RyR2 at S2814 (“Weak” arrow) but increased or “Strong” binding to RyR2 S2814A mimicking dephosphorylated RyR2 at S2814.
