Fig. 1.

ROC curve analysis of SFRP5 for total PCOS. In all PCOS population, the SFRP5 cut-off value was 46.13 ng/ml (AUC 0.960; 95% CI 0.900–0.989; P < 0.0001) to identify PCOS with a sensitivity of 88.06% and specificity of 96.87%. The AMH cut-off value was 3.23 ng/ml (AUC 0.968; 95% CI 0.912–0.993; P < 0.0001) with a sensitivity of 98.51% and specificity of 90.62%. The AUC of combination of SFRP5 and AMH was 0.980 with a sensitivity of 91.04% and specificity of 100% (95% CI 0.930–0.998; P < 0.0001). AUC: area under the curve, ROC: receiver operating characteristic analysis