Table 4.
The Top 30 of significant GO enrichment (biological process, molecular function, and cellular component) of differential expressed mRNAs
| GO enrichment | Fold enrichment | Gene number | P value | GO domain |
|---|---|---|---|---|
| cellular ion homeostasis | 18.832 | 3 | 0.009 | Biological process |
| branching involved in labyrinthine layer morphogenesis | 13.950 | 4 | 0.002 | |
| response to yeast | 12.072 | 5 | 0.001 | |
| activation of transmembrane receptor protein tyrosine kinase activity | 10.462 | 4 | 0.006 | |
| labyrinthine layer blood vessel development | 8.260 | 5 | 0.003 | |
| positive regulation of cytokine production | 7.847 | 6 | 0.001 | |
| negative regulation of viral genome replication | 7.062 | 9 | <0.001 | |
| chemokine-mediated signaling pathway | 6.631 | 15 | <0.001 | |
| regulation of angiogenesis | 6.075 | 6 | 0.003 | |
| positive regulation of peptidyl-threonine phosphorylation | 5.812 | 5 | 0.010 | |
| defense response to fungus | 5.812 | 5 | 0.010 | |
| response to cold | 5.231 | 6 | 0.005 | |
| cell maturation | 5.231 | 6 | 0.005 | |
| cellular defense response | 5.062 | 10 | <0.001 | |
| positive regulation of angiogenesis | 4.913 | 18 | <0.001 | |
| calcium-mediated signaling | 4.308 | 7 | 0.005 | |
| wound healing | 3.923 | 10 | 0.001 | |
| type I interferon signaling pathway | 3.923 | 8 | 0.004 | |
| positive regulation of protein kinase B signaling | 3.737 | 10 | 0.001 | |
| cellular response to interleukin-1 | 3.537 | 8 | 0.007 | |
| immune response | 2.908 | 39 | <0.001 | |
| defense response to virus | 2.853 | 15 | 0.001 | |
| chemotaxis | 2.830 | 11 | 0.006 | |
| azurophil granule | 11.667 | 4 | 0.004 | Cellular component |
| collagen trimer | 3.487 | 10 | 0.002 | |
| chemokine receptor activity | 9.350 | 5 | 0.002 | Molecular function |
| growth factor binding | 5.887 | 5 | 0.010 | |
| chemokine activity | 5.190 | 8 | 0.001 | |
| heparin binding | 3.576 | 18 | <0.001 | |
| receptor activity | 2.930 | 20 | <0.001 |