Table 2.
Univariate analysis and multivariate analysis of factors associated with OS using a Cox regression model for patients underwent CRS in our center. Statistically significant P values are presented in bold-italics. P values that are not statistically significant are presented in in italics
| Variables | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| 95%CI | P value | 95%CI | P value | |
| Tumor deposits | ||||
| None | ||||
| Present | 1.131 (0.589–2.172) | P=0.711 | ||
| Unknown | 0.355 (0.081–1.556) | P=0.169 | ||
| Perineural invasion | ||||
| None | ||||
| Present | 1.233 (0.613–2.480) | P=0.556 | ||
| Unknown | 0.375 (0.114–1.234) | P=0.107 | ||
| Scope Reg LN Sur | ||||
| None | ||||
| Present | 1.785 (0.781–4.079) | P=0.169 | ||
| Unknown | 0.515 (0.105–2.535) | P=0.414 | ||
| Scope Reg LN Sur (Number) | ||||
| <4 | ||||
| ≥4 | 1.536 (0.792–2.978) | P=0.204 | ||
| Unknown | 0.394 (0.090–1.724) | P=0.216 | ||
| HIPEC | ||||
| No | ||||
| Yes | 0.868 (0.479–1.573) | P=0.641 | ||
| Metastatic tumor size | ||||
| ≤15cm | ||||
| >15cm | 2.536 (1.174–5.480) | P=0.018 | ||
| Unknown | 0.711 (0.167–3.024) | P=0.644 | ||
| Number of OM | ||||
| Unilateral | ||||
| Bilateral | 1.956 (0.965–3.967) | P=0.063 | ||
| Unknown | 1.779 (0.394–8.021) | P=0.454 | ||
| PM | ||||
| No | ||||
| Yes | 2.295 (1.170–4.503) | P=0.016 | ||
| PCI | ||||
| ≤10 | ||||
| >10 | 2.807 (1.421–5.544) | P=0.003 | ||
| CA125 | ||||
| ≤ 40 kU/L | ||||
| >40 kU/L | 1.212 (0.603–2.436) | P=0.589 | ||
| unknown | 1.012 (0.411–2.491) | P=0.979 | ||
| CEA | ||||
| ≤30 mg/L | ||||
| >30 mg/L | 0.899 (0.437–1.852) | P=0.773 | ||
| unknown | 0.728 (0.276–1.920) | P=0.521 | ||
| CA199 | ||||
| ≤60 kU/L | ||||
| >60 kU/L | 0.837 (0.397–1.765) | P=0.641 | ||
| unknown | 0.713 (0.271–1.876) | P=0.494 | ||
| CC | ||||
| 0 | ||||
| 1 | 7.412 (2.170–25.317) | P=0.001 | 7.412(2.170-25.317) | P=0.001 |
| 2 | 4.827 (2.235–10.422) | P<0.001 | 4.827(2.235-10.422) | P<0.001 |
| 3 | 143.854 (8.430–2454.725) | P=0.001 | 143.854(8.430-2454.725) | P=0.001 |
| CC | ||||
| 0–1 | ||||
| >1 | 3.782 (1.873–7.637) | P<0.001 | 3.782(1.873-7.637) | P<0.001 |
Abbreviations: N, number; CEA, carcinoembryonic antigen; Scope Reg LN Sur, regional lymph node surgery in surgery; OS, overall survival; HR, hazard ratio; CI, confidence interval