TABLE 3.
The effects of mutations on the secondary structure of protein
| Genotype/properties | SYNE1 (WT) | SYNE1 (p.S4607F) | LDB3 (WT) | LDB3 (p.M456R) | MYH6 (WT) | MYH6 (p.S180Y) |
|---|---|---|---|---|---|---|
| αhelix | 3,845 (77.16%) | 3,846 (77.18%)* | 132 (21.39%) | 132 (21.39%) | 1,479 (76.28%) | 1,473 (75.97%)* |
| ß sheet | 269 (5.40%) | 268 (5.38%)* | 107 (17.34%) | 106 (17.18%)* | 125 (6.45%) | 123 (6.34%)* |
| ß Turn | 230 (4.62%) | 230 (4.62%) | 51 (8.27%) | 52 (8.43%)* | 73 (3.76%) | 69 (3.56%)* |
| Coil | 639 (12.82%) | 639 (12.82%) | 327 (53.00%) | 327 (53.00%) | 262 (13.51%) | 274 (14.13%)* |
*
Showed the changes of the parameters.