Table 2.
Cox hazard regression models for time to death. Stroke events in patients without dementia are the reference category
| Model 1 | Model 2 | Model 3 | Model 4 | |
| Dementia | 1.86 (1.82–1.90)*** | 1.39 (1.36–1.43)*** | 1.26 (1.23–1.29)*** | / |
| Age | 1.09 (1.08–1.09)*** | 1.08 (1.08–1.08)*** | 1.08 (1.08–1.08)*** | 1.08 (1.08–1.08)*** |
| Female sex | 0.92 (0.91–0.94)*** | 0.87 (0.85–0.89)*** | 0.92 (0.90–0.93)*** | 0.92 (0.90–0.93)*** |
| Dependent mobility | / | 1.80 (1.75–1.84)*** | 1.67 (1.63–1.71)*** | 1.67 (1.63–1.71)*** |
| Nursing home placement | / | 1.46 (1.42–1.50)*** | 1.44 (1.40–1.48)*** | 1.43 (1.40–1.47)*** |
| Year of stroke | / | 0.96 (0.96–0.96)*** | 0.95 (0.95–0.96)*** | 0.95 (0.95–0.96)*** |
| CCI | / | / | 1.14 (1.13–1.14)*** | 1.14 (1.13–1.14)*** |
| Vascular dementia | / | / | / | 1.16 (1.08–1.24)*** |
| AD and mixed dementia | / | / | / | 1.23 (1.16–1.31)*** |
| Other or unspecified dementias | / | / | / | 1.28 (1.24–1.31)*** |
| Only patients≤80 years of age | ||||
| Dementia | 2.56 (2.45–2.67)*** | 1.73 (1.65–1.82)*** | 1.47 (1.40–1.54)*** | / |
| Age | 1.08 (1.07–1.08)*** | 1.07 (1.07–1.08)*** | 1.07 (1.07–1.07)*** | 1.07 (1.07–1.07)*** |
| Female sex | 0.92 (0.89–0.95)*** | 0.87 (0.84–0.90)*** | 0.92 (0.88–0.95)*** | 0.91 (0.88–0.95)*** |
| Dependent mobility | / | 2.25 (2.13–2.38)*** | 1.94 (1.84–2.05)*** | 1.94 (1.84–2.05)*** |
| Nursing home placement | / | 1.64 (1.54–1.76)*** | 1.70 (1.59–1.82)*** | 1.69 (1.58–1.81)*** |
| Year of stroke | / | 0.96 (0.96–0.97)*** | 0.95 (0.94–0.95)*** | 0.95 (0.94–0.96)*** |
| CCI | / | / | 1.19 (1.18–1.19)*** | 1.19 (1.18–1.19)*** |
| Vascular dementia | / | / | / | 1.23 (1.09–1.40)*** |
| AD and mixed dementia | / | / | / | 1.46 (1.30–1.64)*** |
| Other or unspecified dementias | / | / | / | 1.50 (1.43–1.59)*** |
| Only patients > 80 years of age | ||||
| Dementia | 1.68 (1.64–1.73)*** | 1.27 (1.24–1.31)*** | 1.18 (1.14–1.21)*** | / |
| Age | 1.09 (1.08–1.09)*** | 1.08 (1.08–1.08)*** | 1.08 (1.08–1.09)*** | 1.08 (1.08–1.09)*** |
| Female sex | 0.92 (0.91–0.94)*** | 0.87 (0.85–0.89)*** | 0.91 (0.89–0.93)*** | 0.91 (0.89–0.93)*** |
| Dependent mobility | / | 1.70 (1.65–1.75)*** | 1.61 (1.56–1.65)*** | 1.61 (1.56–1.65)*** |
| Nursing home placement | / | 1.45 (1.41–1.50)*** | 1.42 (1.37–1.46)*** | 1.42 (1.37–1.46)*** |
| Year of stroke | / | 0.96 (0.96–0.97)*** | 0.95 (0.95–0.96)*** | 0.95 (0.95–0.96)*** |
| CCI | / | / | 1.12 (1.11–1.12)*** | 1.12 (1.11–1.13)*** |
| Vascular dementia | / | / | / | 1.10 (1.01–1.19)*** |
| AD and mixed dementia | / | / | / | 1.16 (1.08–1.25)*** |
| Other or unspecified dementias | / | / | / | 1.19 (1.15–1.22)*** |
Results are presented as hazards ratios (HRs) with 95% CI. *p < 0.05, **p < 0.01, ***p≤0.001 CCI, Charlson comorbidity index. Independent mobility, nursing home placement and CCI are reported prior to stroke.