. 2021 Jun 1;81(3):1211–1229. doi: 10.3233/JAD-210137

Table 6.

Determinants of verbal episodic memory at the end of study: LnHVLT-DR_2, placebo group^*

Variable	Pearson correlation		Multiple regression^#
(n = 82–112)
			Model 1		Model 2		Model 3		Model 4		Model 5		Model 6
	β	p	β	p	β	p	β	p	β	p	β	p	β	p
LntHcy-_1	–0.37	0.000
LnPOase_1	–0.04	0.710							–0.54	0.053	–0.16	0.192
LnPhAcase_1	0.01	0.942	–0.32	0.012	–0.29	0.015
PON1-Q192R	0.00	0.998	–0.14	0.231			–0.05	0.655	0.40	0.125
LnFe_1	–0.19	0.090
LnAtrophy_rate	–0.30	0.008	–0.24	0.053	–0.21	0.054	–0.22	0.089	–0.26	0.047	–0.24	0.068	–0.22	0.087
LnHVLT-DR_1	0.55	0.000	0.46	0.000	0.44	0.001	0.38	0.004	0.41	0.002	0.40	0.002	0.38	0.003
APOE	–0.21	0.038
BDNF V66M	0.05	0.641	0.31	0.010	0.29	0.015	0.31	0.015	0.38	0.004	0.36	0.005	0.31	0.010
Age	–0.33	0.000
Sex	0.14	0.167
			F = 4.68,		F = 5.23,		F = 3.93,		F = 4.14,		F = 4.41,		F = 4.93,
			p = 0.000,		p = 0.000,		p = 0.000,		p = 0.000,		p = 0.000,		p = 0.000,
			Adjusted		Adjusted		Adjusted		Adjusted		Adjusted		Adjusted
			R² = 0.37		R² = 0.37		R² = 0.29		R² = 0.34		R² = 0.32;		R² = 0.32

^*Ln, natural logarithm; PhAcase, phenylacetate hydrolase; POase, paraoxonase; _1, baseline; _2, end of study. ^# Adjusted for sex, LnAnti-N-Hcy_1, LntHcy_1, and APOE genotype. LntHcy_1 was not significant in any of the models.