Table 8.
Variable | Pearson correlation | Multiple regression# | ||||||||||||
(n = 78–109) | ||||||||||||||
Model 1 | Model 2 | Model 3 | Model 4 | Model 5 | Model 6 | |||||||||
β | p | β | p | β | p | β | p | β | p | β | p | β | p | |
LntHcy-_1 | –0.31 | 0.001 | –0.20 | 0.013 | –0.19 | 0.013 | –0.19 | 0.025 | –0.19 | 0.019 | –0.19 | 0.022 | –0.18 | 0.026 |
LnPOase_1 | –0.17 | 0.107 | –0.33 | 0.028 | –0.06 | 0.336 | ||||||||
LnPhAcase_1 | –0.14 | 0.162 | –0.18 | 0.008 | –0.16 | 0.011 | ||||||||
PON1-Q192R | –0.04 | 0.702 | –0.06 | 0.417 | 0.00 | 0.963 | 0.29 | 0.047 | ||||||
LnFA_1 | –0.14 | 0.157 | –0.20 | 0.020 | –0.20 | 0.017 | –0.21 | 0.020 | –0.19 | 0.032 | –0.24 | 0.005 | –0.24 | 0.006 |
LnAnti-N–Hcy_1 | –0.01 | 0.912 | –0.15 | 0.041 | –0.15 | 0.027 | –0.17 | 0.025 | –0.14 | 0.047 | –0.15 | 0.036 | –0.17 | 0.017 |
LnAtrophy_rate | –0.35 | 0.002 | –0.24 | 0.001 | –0.24 | 0.001 | –0.22 | 0.005 | –0.23 | 0.002 | –0.21 | 0.005 | –0.22 | 0.004 |
LnSDMT _1 | 0.80 | 0.000 | 0.65 | 0.000 | 0.67 | 0.000 | 0.67 | 0.000 | 0.65 | 0.000 | 0.67 | 0.000 | 0.68 | 0.000 |
Age | –0.35 | 0.000 | ||||||||||||
F = 23.20, | F = 27.39, | F = 22.18, | F = 22.04, | F = 24.03, | F = 27.23, | |||||||||
p = 0.000, | p = 0.000, | p = 0.000, | p = 0.000, | p = 0.000, | p = 0.000, | |||||||||
Adjusted | Adjusted | Adjusted | Adjusted | Adjusted | Adjusted | |||||||||
R2 = 0.78 | R2 = 0.79 | R2 = 0.76 | R2 = 0.78 | R2 = 0.77; | R2 = 0.77 |
*Ln, natural logarithm; PhAcase, phenylacetate hydrolase; POase, paraoxonase; _1, baseline; _2, end of study. # Adjusted for sex, and LnTG_1.