Table 1.

The binding free energies (ΔG_binding) of Aβ and peptide-Aβ complexes with the MM_GBSA method and the contributions of each force

Contribution	WRW		FWW		RRY
	mean	SEM	mean	SEM	mean	SEM
ΔEelec	–127.8622	31.7238	–39.2240	32.8006	–227.0111	23.7255
ΔEvdw	–31.5055	3.5854	–32.2817	5.2270	–23.3137	4.9036
ΔEgas	–159.3677	31.6756	–71.5057	35.9271	–250.3248	24.3890
ΔGnonpolarp	–4.7953	0.3023	–5.7332	0.6516	–3.7533	0.4370
ΔGGB	141.7892	32.1894	52.2206	33.8447	248.2323	23.5212
ΔGsolvation	136.9939	32.2142	46.4874	33.4034	244.4790	23.4184
ΔGbinding	–22.3738		–25.0183		–5.8458
Contribution	RWY		WWW		RGD		WRY
	mean	SEM	mean	SEM	mean	SEM	mean	SEM
ΔEelec	–105.6885	21.4133	15.1222	24.6331	–134.6431	31.9144	–188.2275	22.2736
ΔEvdw	–24.5772	4.4112	–32.8116	5.4779	–13.2767	2.6566	–41.7505	4.8319
ΔEgas	–130.3117	22.3945	–17.6893	27.6163	–147.9199	32.3657	–229.9781	25.0730
ΔGnonpolarp	–4.2947	0.4543	–5.4620	0.6199	–2.7636	0.2908	–6.4817	0.3609
ΔGGB	118.0171	20.9540	–3.1101	24.9175	142.9110	30.3403	202.4201	22.6944
ΔGsolvation	113.7224	20.7604	–8.5721	24.6319	140.1474	30.1113	195.9385	22.5127
ΔGbinding	–16.5893		–26.2614		–7.7724		–34.0396