Table 3.
Adjusted odds ratios of adverse outcomes at 3-month according to eosinophil changes after Intravenous thrombolysis in different TOAST subtypes.
| Outcomes | Increase or no change | 0< decrease ≤25% | 25%< decrease ≤50% | 50%< decrease ≤75% | 75%< decrease ≤100% | Each 10% decrease in Eosinophils |
|---|---|---|---|---|---|---|
| Poor outcome | ||||||
| Cardioembolism | 1 | 3.930 (0.668–23.123) | 5.161 (0.956–27.590) | 11.031 (2.129–57.153) | 11.453 (2.661–49.283) | 1.203 (1.087–1.333) |
| Large artery atherosclerosis |
1 | 0.312 (0.086–1.134) | 1.699 (0.700–4.120) | 0.969 (0.313–3.001) | 1.496 (0.599–3.737) | 1.017 (0.977–1.059) |
| Small artery occlusion | 1 | 0.603 (0.033–10.925) | NA | NA | NA | 0.935 (0.767–1.141) |
| Other/undetermined | 1 | 4.888 (0.337–71.010) | 1.544 (0.100–23.885) | 0.828 (0.003–225.626) | 5.126 (0.528–46.242) | 1.030 (0.954–1.112) |
| Death | ||||||
| Cardioembolism | 1 | 10.622 (0.650–173.592) | 1.306 (0.049–34.813) | 4.666 (0.359–60.680) | 20.037 (1.984–202.375) | 1.231 (1.054–1.437) |
| Large artery atherosclerosis |
1 | NA | NA | 4.141 (0.403–42.588) | 2.420 (0.283–20.678) | 1.006 (0.900–1.125) |
| Small artery occlusion | NA | NA | NA | NA | NA | NA |
| Other/undetermined | NA | NA | NA | NA | NA | NA |
Adjusted for age, sex, current smoking, history of hypertension, atrial fibrillation, stroke, triglycerides and admission NIHSS scores (Model 3 in Table 2 ).
NA due to lack of outcome events in this subgroup.