Table 4.

Reclassification and discrimination statistics for adverse outcomes by eosinophils changes after intravenous thrombolysis in AIS patients.

	C-statistics		Continuous NRI		IDI
	Estimate(95% CI)	p value	Estimate(95% CI)	p value	Estimate(95% CI)	p value
Predict for poor outcome (Total Patients, n = 623)
Conventional model	0.847 (0.815–0.874)		Ref.		Ref.
Conventional model + △Eosinophil	0.853 (0.822–0.880)	0.304	0.533 (0.358–0.709)	<0.001	0.022 (0.010–0.034)	<0.001
Predict for death (Total Patients, n = 623)
Conventional model	0.932 (0.908–0.950)		Ref.		Ref.
Conventional model + △Eosinophil	0.950 (0.929–0.966)	0.094	1.010 (0.772–1.248)	<0.001	0.069 (0.029–0.110)	<0.001
Predict for poor outcome (Cardioembolic Stroke Only, n = 187)
Conventional model	0.886 (0.829–0.929)		Ref.		Ref.
Conventional model + △Eosinophil	0.907 (0.854–0.946)	0.059	0.667 (0.389–0.944)	<0.001	0.053 (0.020–0.086)	0.001
Predict for death (Cardioembolic Stroke Only, n = 187)
Conventional model	0.922 (0.872–0.957)		Ref.		Ref.
Conventional model + △Eosinophil	0.942 (0.897–0.972)	0.067	0.971 (0.685–1.256)	<0.001	0.080 (0.033–0.126)	<0.001

The conventional model included age, sex, current smoking, history of hypertension, atrial fibrillation, stroke, triglycerides and admission NIHSS scores.

△Eosinophil enter the model in the form of categorical variable (5 groups displayed in Tables 1– 3 ).