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. 2021 Jul 7;12:702374. doi: 10.3389/fgene.2021.702374

TABLE 2.

Levels of C5DC in the blood, C5DC/C8 ratios and urinary GA in each of the three groups.

C5DC (μmol/L) C5DC/C8 GA (mmol/mol Cr)



Reference range 0.02∼0.25 0.10∼2.50 0∼8
Before treatment After treatment Before treatment After treatment Before treatment After treatment
All patients 0.92 (0.11∼5.13) 0.86 (0.06∼4.68) 22.04 (1.6∼218) 11.86 (0.46∼73.45) 562.76 (0.12∼4,514) 201 (0.96∼1,099)
NBS patients 1.64 (0.11∼3.2) 1.77 (0.75∼4.68) 19.81 (1.6∼214) 12.54 (2.71∼40.57) 547.51 (1.92∼2,477) 230.85 (45.59∼378.82)
Clinical patients 0.83 (0.13∼5.13) 0.60 (0.06∼4.49) 22.29 (2.58∼218) 11.712 (0.46∼73.45) 578 (0.12∼4,514) 157.7 (0.96∼1,099)
P(NBS–Clinical) 0.148 0.002 0.973 0.657 0.947 0.702
P(all patients)* 0.012 <0.001 <0.001
P(NBS)* 0.477 0.011 0.012
P(Clinical)* 0.014 <0.001 <0.001

P value for each group before and after treatment.

NBS, newborn screening.