Table 4.
Mean proportion discoveries for LRT and Wald statistics of the Negative Binomial mixed model when using the asymptotic 
(“LRT” and “W”, respectively) and their corresponding bootstrap-based null distribution (“LRT-boot” and “W-boot”, respectively) for testing 
versus 
or 
. We have made comparisons with the 
-test statistic in limma-voom approach (“F-voom”) and LRT and 
-test statistic in edgeR (‘LRT-edgeR’ and ‘W-edgeR’, respectively)
|
LRT | LRT-edgeR | F-edgeR | W | LRT-boot | W-boot | F-voom |
|---|---|---|---|---|---|---|---|
| 0.5 | 0.482 | 0.000 | 0.000 | 0.511 | 0.441 | 0.441 | 0.003 |
| 1.5 | 0.514 | 0.694 | 0.665 | 0.526 | 0.506 | 0.505 | 0.503 |
| 2.0 | 0.492 | 0.692 | 0.668 | 0.528 | 0.506 | 0.506 | 0.554 |