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. 2021 Jul 7;9:691560. doi: 10.3389/fcell.2021.691560

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Copyright © 2021 Bender, Fietz, Richter and Stanojlovic.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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GFAP signal intensity in the hippocampal dentate gyrus and CA1 region of wildtype and Thy1-aSyn mice. (A–D) Immunofluorescence for GFAP (red) and DAPI staining (blue) and merged images of 6 and 16-month-old wildtype [WT, (A,B)] and 6 and 16-month-old Thy1-aSyn [asyn, (C,D)] mice. (E–H) Mean GFAP pixel intensity in the subgranular zone (SGZ), molecular layer (ML), polymorph layer (PL) and CA1 region of 6- and 16-month (mo)-old wildtype (WT) and Thy1-aSyn (asyn) mice. Data represent mean ± SEM. (n = 6/group; Student’s t-test; ^∗p < 0.05; ^∗∗p < 0.01). Scale bars, 50 μm.