Table 2.
Summary of preparation and formulation of PRP in the included studies.
| Study | Trial/control | Volume of collected blood | Anticoagulant | Centrifugal method | Leukocyte-poor PRP |
|---|---|---|---|---|---|
| Filardo 2012 [14] | PRP vs. HA | 150 ml | Not reported | Double-spin methodology | No |
| Patel 2013 [9] | PRP vs. saline | 100 mL | Citrate phosphate dextrose and adenine | Single-spin methodology | Yes |
| Raeissadat 2015 [14] | PRP vs. HA | 35-40 mL | Not reported | Double-spin methodology | No |
| Filardo 2015 [6] | PRP vs. HA | 150 mL | Not reported | Double-spin methodology | No |
| Cole 2016 [18] | PRP vs. HA | 60 mL | Not used | Double-spin methodology | Yes |
| Simental 2016 [27] | PRP vs. acetaminophen | 27 mL | Sodium citrate | Double-spin methodology | Yes |
| Forogh 2016 [16] | PRP vs. corticosteroid | 20 mL | Citrate dextrose | Double-spin methodology | No |
| Jubert 2017 [10] | PRP vs. corticosteroid | 60 mL | Citrated dextrose | Single-spin methodology | No |
| Su 2018 [21] | PRP vs. HA | 45 mL | Sodium citrate | Double-spin methodology | No |
| Ahmad 2018 [11] | PRP vs. HA | 8 mL | Not reported | Single-spin methodology | No |
| Uslu 2018 [22] | PRP vs. corticosteroid | 18 mL | Citrate dextrose | Single-spin methodology | No |
| Lisi 2018 [19] | PRP vs. HA | 20 mL | Citrate dextrose | Single-spin methodology | No |
| Buendía 2018 [23] | PRP vs. HA vs. NSAIDs | 60 mL | Not reported | Double-spin methodology | Yes |
| Wu 2018 [19] | PRP vs. saline | 10 mL | Not reported | Dingle-spin methodology | No |
| Louis 2018 [24] | PRP vs. HA | 52.5 mL (for men) or 37.5 mL (for women) | Citrate dextrose | Double-spin methodology | No |
| Lin 2019 [3] | PRP vs. HA vs. saline | 10 mL | Not used | Dingle-spin methodology | Yes |
| Di Martino 2019 [25] | PRP vs. HA | 150 mL | Not reported | Double-spin methodology | No |
| Elik 2019 [26] | PRP vs. saline | 10 mL | Sodium citrate | Double-spin methodology | No |
| Huang 2019 [28] | PRP vs. HA vs. corticosteroid | 8 mL | Not reported | Single-spin methodology | Yes |