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. Author manuscript; available in PMC: 2021 Jul 21.
Published in final edited form as: ACS Chem Neurosci. 2019 Jan 31;10(4):2012–2021. doi: 10.1021/acschemneuro.8b00340

Figure 4.

Figure 4.

Effects of administration of cumulative doses of R-MOD, each derivative compound and cocaine on the maximum elicited DA peak (DAMax), reported as a percentage of baseline DAMax. Data represents mean ± SEM (n = 4–6). Baseline values: Cocaine, 0.13 ± 0.02 μM (n=6); R-MOD, 0.38 ± 0.08 μM (n=4); JJC8-016, 0.43 ± 0.14 μM (n=5); JJC8-088, 0.29 ± 0.13 μM (n=4); JJC8-091, 0.26 ± 0.06 μM (n=4). DAMax baseline values were not found to be significantly different between groups or from vehicle treatments (SI Tables 4 and 5).