Table 1.
Basic characteristic of research.
| No | Author/year | Study Type | Country | N (3090) | Age | Sex M/F (n) |
Admitted to ICU (n = 829) | ARDS (n = 779) | On ECMO (n = 527) | Type of ECMO | Overall mortality (%) | ECMO Outcome |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Abou-Arab et al./2020 [7] | Case report | France | 2 | 59 67 |
F M |
2 | 2 | 2 | N/A VV |
N/A | N/A |
| 2 | Barrasa et al./2020 [8] | Retrospective | Spain | 48 | 63 (median) | M (27) F (21) |
48 | 48 | 1 | VV | 6 (15) | N/A |
| 3 | Bemtgen et al./2020 [9] | Case report | Germany | 1 | 52 | M | 1 | 1 | 1 | VA to VV | N/A | on ECMO |
| 4 | Chen et al./2020 [10] | Retrospective | China | 99 | 55.5 (mean) | M (67) F (32) |
23 | 17 | 3 | N/A | 11 (11) | 1 death |
| 5 | Firstenberg et al./2020 [11] | Case report | USA | 1 | 51 | M | 1 | 1 | 1 | VV | N/A | discharged day 28 |
| 6 | Giani et al./2020 [12] | Case report | Italy | 1 | 66 | M | 1 | 1 | 1 | VV | N/A | N/A |
| 7 | Guan et al./2020 [13] | Cross sectional | China | 1099 | 47 (median) | M (640) F (459) |
55 | 37 | 5 | N/A | 14 (1.4) | 5 on ECMO meet primary endpoints |
| 8 | Hartman et al./2020 [14] | Case report | USA | 1 | 44 | M | N/A | N/A | 1 | VV | N/A | taken off ECMO day 7 |
| 9 | Huang et al./2020 [15] | Cross sectional | China | 41 | 49 (median) | M (30) F (11) |
13 | 12 | 2 | N/A | 6 (14.6) | N/A |
| 10 | Jacobs et al./2020 [16] | Cross sectional | USA | 32 | 52.4 (mean) | M (22) F (10) |
N/A | N/A | 32 | VA VAV VV |
10 (31.3) | 10 deaths, 5 weaned off, 17 on ECMO |
| 11 | Japan ECMsOne/ 2020 [17] | Cross sectional | Japan | 26 | 71 (mean) | N/A | N/A | N/A | 26 | N/A | N/A | 16 weaned off, 6 extubated and referred for rehabilitation, 10 on ECMO. |
| 12 | Kato et al./ 2020 [18] | Case series | Japan | 70 | 67 (mean) | M (47) F (23) |
N/A | N/A | 2 | VV | 2 (14.8) | 2 weaned off |
| 13 | Li et al./2020 [1] | Case series | China | 8 | 65 (mean) | M (6) F (2) |
N/A | N/A | 8 | VV VA |
N/A | 4 deaths, 3 weaned off, 1 on ECMO |
| 14 | Loforte et al./ 2020 [19] | Observational | Italy | 59 | 49 (mean) | M (4) F (55) |
59 | 59 | 4 | VV | 1 (25) | 1 death, 3 weaned off |
| 15 | Marullo et al./ 2020 [3] | Retrospective | Europe | 333 | 51.8 (mean) | M (285) F (48) |
N/A | N/A | 333 | VA VAV VV VVV |
57 (17.1) | 57 deaths, 54 weaned off |
| 16 | Nakamura et al./ 2020 [20] | Case report | Japan | 1 | 45 | M | 1 | 1 | 1 | VV | N/A | discharged |
| 17 | Ruan et al./ 2020 [21] | Retrospective | China | 150 | 67 (median) | M (102) F (48) |
41 | 62 | 7 | N/A | 68 (48.3) | 7 deaths |
| 18 | Schmiady et al./ 2020 [22] | Case report | Swiss | 1 | 54 | F | 1 | 1 | 1 | VV | N/A | N/A |
| 19 | Shen et al./ 2020 [23] | Case series | China | 5 | 60 (mean) | M (3) F (2) |
5 | 5 | 1 | N/A | N/A | weaned off |
| 20 | Sultan et al./ 2020 [24] | Case series | USA | 10 | 31–62 | M (7) F (3) |
N/A | 10 | 10 | VV | 1 (10) | 1 death, 3 weaned off |
| 21 | Takeda et al./ 2020 [25] | LTE | Japan | 26 | 71 | N/A | N/A | N/A | 26 | N/A | N/A | 16 weaned off, 10 on ECMO |
| 22 | Tang et al./ 2020 [26] | Retrospective case control | China | 179 | 62 (median) | M (105) F (74) |
73 | 73 | 10 | N/A | 21 (28.3) | N/A |
| 23 | Taniguchi et al./ 2020 [27] | Case report | Japan | 1 | 72 | F | 1 | 1 | 1 | VV | N/A | Weaned off ECMO day 12 |
| 24 | Tavazzi et al./ 2020 [28] | Case report | Italy | 1 | 69 | N/A | N/A | 1 | 1 | VA | N/A | Patient died |
| 25 | Yousefzai et al./ 2020 [29] | Case report | USA | 1 | 56 | M | 1 | 1 | 1 | VA | N/A | Weaned off ECMO |
| 26 | Wang et al./ 2020 [30] | Retrospective | China | 138 | 56 (median) | M (75) F (63) |
36 | 22 | 4 | N/A | 6 (4.3) | N/A |
| 27 | Wu et al./ 2020 [31] | Retrospective | China | 201 | N/A | N/A | 53 | 84 | 1 | N/A | 44 (22.9) | Patient died |
| 28 | Yang et al./ 2020 [32] | Retrospective | China | 52 | 59.7 (median) | M (35) F (17) |
52 | 35 | 6 | N/A | 32 (4.5) | 5 deaths |
| 29 | Yu et al./ 2020 [33] | Cross sectional | China | 226 | 64 (mean) | M (139) F (87) |
226 | 161 | 14 | N/A | N/A | 9 death |
| 30 | Zangrillo et al./ 2020 [34] | Case series | Italy | 73 | 61 (median) | M (61) F (12) |
73 | 73 | 5 | N/A | 17 (23.3) | N/A |
| 31 | Zeng et al./ 2020 [35] | Case series | China | 12 | 50.9 (mean) | M (11) F (1) |
12 | 12 | 12 | N/A | 5 (41.6) | 5 deaths, 3 weaned off, 4 on ECMO, 2 coma |
| 32 | Zhan et al./ 2020 [36] | Case report | China | 1 | 54 | M | N/A | N/A | 1 | VV | N/A | discharged |
| 33 | Zhou et al./ 2020 [37] | Retrospective | China | 191 | 56 (median) | M (119) F (72) |
50 | 59 | 3 | N/A | 54 (28.3) | 3 deaths |
Abbreviations: VA veno-arterial; VV veno-venous;, N/A: not available.