Table 1.
Characteristics of 85 patients with triple-negative breast cancer who received neoadjuvant systemic therapy
Characteristic | Study population | pCR | Non-pCR |
---|---|---|---|
No. of patients | 85 | 37/85 (44) | 48/85 (56) |
Age (years) | |||
Mean ± SD | 51.8 ± 13 | 54.3 ± 13.8 | 49.9 ± 12.39 |
Median (range) | 51 (26–78) | 57 (27–78) | 47 (26–75) |
Longest tumor diameter (cm) | |||
Mean ± SD | 4.57 ± 2.9 | 3.6 ± 2.18 | 5.3 ± 3.3 |
Median (range) | 3.8 (1.3–9.8) | 3 (1.3–4.4) | 4.25 (1.6–9.8) |
Tumor histological type | |||
IDC grade II | 10/85 (12) | 2/37 (5) | 8/48 (17) |
IDC grade III | 72/85 (85) | 35/37 (95) | 37/48 (77) |
Metaplastic | 3/85 (3) | 0/37 (0) | 3/48 (6) |
Necrotic tumor histological type | |||
IDC grade II | 5/85 (6) | 1/37 (3) | 4/48 (8) |
IDC grade III | 32/85 (38) | 16/37 (43) | 16/48 (33) |
Metaplastic | 2/85 (2) | 0/37 (0) | 2/48 (4) |
Tumor classification on DCE imaging | |||
Non-necrotic (solid) | 46/85 (54) | 20/37 (54) | 26/48 (54) |
Necrotic | 39/85 (46) | 17/37 (46) | 22/48 (46) |
Type of surgery | |||
Total mastectomy | 47/85 (55) | 21/37 (57) | 28/48 (58) |
Conservative surgery | 38/85 (45) | 16/37 (43) | 20/48 (42) |
Data are number of patients (percent) unless otherwise indicated
DCE dynamic contrast-enhanced, IDC infiltrating ductal carcinoma, pCR pathological complete response, SD standard deviation, TNBC triple-negative breast cancer