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. 2021 Jul 6;11:657867. doi: 10.3389/fcimb.2021.657867

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Copyright © 2021 Gao, Zhu, Kong, Xia, Li, Zhu, Zhang, Liu, Zhong, Yang, Chen, Qin and Qin

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Relative abundances of bacterial and viral species in control (colored in green), adenoma (colored in amber), and CRC (colored in dubonnet) groups. (A) Top 10 bacteria showed increased or decreased relative abundance in the CRC group than in the control group. The vertical axis represents relative abundance. (B) Heatmap of the top 10 bacteria that showed increased (top 10) or decreased (lower 10) relative abundance in the CRC group compared with that in the control group. (C) The 15 viruses that were different in relative abundance between the control and CRC groups, including 11 enriched and top 4 depleted in the CRC group. (D) Heatmap of the 15 viruses that were different in relative abundance between the control and CRC groups.