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. 2021 Jul 6;11:657867. doi: 10.3389/fcimb.2021.657867

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Copyright © 2021 Gao, Zhu, Kong, Xia, Li, Zhu, Zhang, Liu, Zhong, Yang, Chen, Qin and Qin

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Co-occurrence networks of the marker species in the control (A), adenoma (B), and CRC (C) groups. Each microbial species is marked by its affiliating phylum, which is shown in the top right. A microbial species and cooccurrence relationship are indicated by a node and an edge, respectively. A connection (line between dots) indicates a significant (FDR < 0.05) correlation. The size of each node is proportional to the relative abundance of the species. Lines between nodes indicate positive correlations (green) or negative correlations (red).