Table 3.
Echocardiographic parameters of patients
| TTE at baseline N = 40 |
TTE at follow-up N = 40 |
p value | |
|---|---|---|---|
| LV dimensions, median (IQR) | |||
| Indexed LVEDd (mm/m2) | 24 (21 to 26) | 23 (22 to 26) | 0.976 |
| Indexed LV mass (g/m2) | 83 (68 to 92) | 71 (61 to 95) | 0.036 |
| LV systolic function median (IQR) | |||
| All EF % (n = 40) | 60.0 (55.5 to 60.0) | 58.0 (54.3 to 60.4) | 0.544 |
| Triplane EF–triplane EF (n = 20) | 57 (52.3 to 59.0) | 55.0 (53.3 to 58) | 0.793 |
| Biplane EF–biplane EF (n = 5) | 63.0 (59.5 to 66.0) | 61.0 (58.5 to 62.0) | 0.221 |
| Eyeball EF–average EF (n = 11) | 60.0 (60.0 to 60.0) | 60.0 (56.5 to 63.0) | 0.475 |
| Eyeball EF–eyeball EF (n = 4) | 60.0 (60.0 to 60.0) | 60.0 (60.0 to 60.0) | > 0.99 |
| 3D EF % (n = 32) | – | 61 (55.5 to 64) | – |
| Global longitudinal strain (%) | n = 21 | n = 28 | |
| − 18.5 (− 19.5 to − 17.0) | − 19.1 (− 20.8 to − 18.2) | 0.067 | |
| LV diastolic function median (IQR) | |||
| E/e′ ratio | n = 40 | n = 40 | |
| 7.3 (6.0 to 9.8) | 7.5 (5.9 to 8.8) | 0.898 | |
| RV dimension and function median (IQR) | |||
| RV basal diameter (mm) | n = 30 | n = 33 | |
| 39 (33 to 41) | 34 (30 to 38) | 0.002 | |
| TAPSE (mm) | n = 40 | n = 39 | |
| 23 (19 to 27) | 22 (20 to 25) | 0.181 | |
| RV S’ (cm/s) | n = 35 | n = 38 | |
| 14 (12 to 18) | 13 (11 to 15) | 0.01 | |
| Other parameters | |||
| Normal LV and RV volumes and function** | 67.5% | 82.5% | 0.07* |
| Abnormal LVEF (< 52%) | 12.5% | 5.0% | 0.25* |
| Abnormal GLS (> − 18%) | 38.1% | 17.9% | 0.125* |
All values were tested with a Wilcoxon signed-rank test, except for (*) which was done with a McNemar test. Values are in median and interquartile range, or n (%)
E/e′ early mitral inflow velocity/mitral annular early diastolic velocity, EF ejection fraction, IQR interquartile range, LV left ventricular, LVEDd left ventricular end-diastolic dimension, LVESd left ventricular end-systolic dimension, LVEF LV ejection fraction, RV right ventricular, RV S’ right ventricular systolic excursion velocity, TAPSE tricuspid annular plane systolic excursion, TTE transthoracic echocardiogram
**Normal TTE was defined as: LVEF ≥ 52%, GLS ≤ − 18%, TAPSE ≥ 17 mm, RV S’ ≥ 10 cm/s, E/e′ ratio ≤ 14, indexed LVmass ≤ 115 g/m2, Indexed LVEDd ≤ 31 mm and RV basal diameter ≤ 42 mm