Table 3.

Outer Setting: determinants, tailoring, and identification of key aspects for implementation planning.

Construct and study results	Considerations regarding determinants	Tailoring and key aspects
Patient Needs and Resources: InvolveMe could potentially contribute to less anxiety	Facilitator: HCPsa described patients being worried and anxious early in the disease trajectory. InvolveMe could be beneficial to patients in terms of increased information and thereby potentially help patients avoid or experience less anxiety.	Tailoring: to provide the intervention as early as possible to patients
Patient Needs and Resources: patient’s motivation to use InvolveMe	Facilitator: it can be difficult to reach HCPs on the telephone. InvolveMe may have the potential to represent a place where patients can get in contact with HCPs.	Key aspect: motivated patients could contribute to HCPs implementing InvolveMe
Patient Needs and Resources: patient acceptance—use of a patient portal	Facilitator: the potential for intervention integration into a patient portal seemed acceptable. This supports findings from the development study [41].	Key aspect: intervention acceptance and adoption
Patient Needs and Resources: patient acceptance—use of a digital health service	Barrier: HCPs described being concerned that InvolveMe might be technically demanding for some patients. Therefore, InvolveMe was designed to be a voluntary supplement to standard care, not a replacement. The assessment in InvolveMe can act as preparation before consultations. To make this clear to all patients, relevant information should be provided.	Tailoring: provide patients with tailored information about the intervention

^aHCP: health care provider.