Table 1.
Basal Characteristics of Included Patients
| Variable | All patients (n = 9386) | VTE group (n = 202) | Non-VTE group (n = 9184) | p* |
|---|---|---|---|---|
| Age (median [IQR]), years | 66.7 [55.8–79.0] | 69.4 [59.3–77.5] | 68.4 [55.7–77.0] | 0.4928 |
| Male sex, n (%) | 5356 (57.1) | 121 (60.2) | 5235 (57.1) | 0.4152 |
| HBP, n (%) | 4695 (50) | 101 (50.0) | 4594 (49.9) | 0.9999 |
| DM, n (%) | 1749 (18.6) | 29 (14.4) | 1720 (18.7) | 0.9637 |
| Dyslipidemia, n (%) | 3667 (39.1) | 8 (43.3) | 3580 (39.1) | 0.2537 |
| Alcohol abuse, n (%) | 419 (4.4) | 15 (7.7) | 404 (4.5) | 0.0575 |
| Smoking, n (%) | 0.5911 | |||
| Former smoker | 2193 (23.4) | 51 (25.9) | 2142 (24.4) | |
| Current smoker | 475 (5) | 13 (6.6) | 462 (5.3) | |
| Dependence, n (%) | 0.1964 | |||
| Absent/mild | 7802 (83.1) | 175 (87.9) | 7627 (84.0) | |
| Moderate | 846 (9.0) | 11 (5.5) | 835 (9.2) | |
| Severe | 631 (6.7) | 13 (6.5) | 618 (6.8) | |
| Atrial fibrillation, n (%) | 984 (10.5) | 9 (4.5) | 975 (10.6) | 0.0064 |
| Chronic anxiety, n (%) | 753 (8) | 20 (9.9) | 733 (8.0) | 0.3941 |
| Chronic depression, n (%) | 981 (10.5) | 29 (14.4) | 952 (10.4) | 0.0879 |
| Obesity, n (%) | 1795 (19.0) | 49 (25.8) | 1746 (20.7) | 0.1065 |
| Neurodegenerative disease, n (%) | 801 (8.5) | 13 (6.5) | 788 (8.6) | 0.3479 |
| Angina, n (%) | 321(3.4) | 6 (3.0) | 315 (3.4) | 0.8701 |
| CHF, n (%) | 615 (6.5) | 11 (5.5) | 604 (6.6) | 0.6135 |
| COPD, n (%) | 599 (6.3) | 10 (5.0) | 589 (6.4) | 0.4831 |
| Asthma, n (%) | 720 (7.6) | 13 (6.5) | 410 (7.7) | 0.6014 |
| TIA, n (%) | 420 (4.4) | 10 (5.0) | 410 (4.5) | 0.8796 |
| Previous IS, n (%) | 246 (2.6) | 7 (3.5) | 239 (2.6) | 0.5941 |
| Residual hemiplegia, n (%) | 151 (1.6) | 4 (2.0) | 147 (1.6) | 0.8819 |
| Dementia, n (%) | 893 (9.5) | 17 (8.4) | 876 (9.6) | 0.6703 |
| PVD, n (%) | 413 (4.4) | 11 (5.5) | 402 (4.4) | 0.5826 |
| CLD, n (%) | 253 (0.2) | 245 (2.6) | 8 (3.9) | 0.3709 |
| CKD, n (%) | 545 (5.8) | 11 (5.5) | 534 (5.8) | 0.9372 |
| Active cancer, n (%) | 532 (5.6) | 21 (10.4) | 511 (5.6) | 0.0054 |
| CTD, n (%) | 225 (2.3) | 7 (3.5) | 218 (2.4) | 0.4375 |
| HIV infection, n (%) | 63 (0.6) | 0 (0) | 63 (0.7) | 0.9999 |
| OSAS, n (%) | 575 (6.1) | 15 (7.5) | 560 (6.1) | 0.5313 |
| CCI, Med. (IQR) | 1 [0–2] | 1 [0–2] | 1 [0–2] | 0.4388 |
| CCI ≥3, n (%) | 1515 (16.1) | 36 (18.2) | 1479 (16.5) | 0.5814 |
VTE, venous thromboembolism; HBP, chronic high blood pressure; DM, diabetes mellitus; CHF, chronic heart failure; COPD, chronic obstructive pulmonary disease; TIA, transient ischemic accident; IS, ischemic stroke; PVD, peripheral vascular disease; CLD, chronic liver disease; CKD, chronic kidney disease; CTD, connective tissue disease; HIV, human immunodeficiency virus; OSAS, obstructive sleep apnea syndrome; CCI, age-adjusted Charlson Comorbidity Index; Med, median; IQR, interquartile range
*Comparison of VTE vs. non-VTE groups