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. 2021 Jul 7;9:677541. doi: 10.3389/fbioe.2021.677541

TABLE 1.

Baseline characteristics of the patient.

PVRP group (n = 11) Control group (n = 11) p
Gender
Male (n, %) 9 (82%) 9 (82%) 1.000
Female (n, %) 2 (18%) 2 (18%)
Age
M ± SD (years) 47 ± 18 52 ± 24 0.632
Comorbidities
Yes (n, %) 6 (55%) 6 (55%) 1.000
No (n, %) 5 (45%) 5 (45%)
Regular medicine intake
Yes (n, %) 3 (27%) 6 (55%) 0.387*
No (n, %) 8 (73%) 5 (45%)
Allergies
Yes (n, %) 5 (45%) 4 (36%) 1.000*
No (n, %) 6 (55%) 7 (64%)
Coagulopathy
Yes (n, %) 2 (18%) 1 (9%) 1.000*
No (n, %) 9 (82%) 10 (91%)
Smoking
Yes (n, %) 2 (18%) 5 (45%) 0.361*
No (n, %) 9 (82%) 6 (55%)
Alcohol consumption
Yes (n, %) 10 (91%) 7 (64%) 0.311*
No (n, %) 1 (9%) 4 (36%)
Time to treatment
Mdn (day–years) 2,688–7.4 3,172–8.7 0.116**
Time from surgery
Mdn (days–years) 4,644–12.7 5,224–14.3 0.573**
COMQ-12 score
Mdn 33 34 0.977**

Time to treatment – the time from the beginning of the problems due to chronic postoperative temporal bone cavity inflammation to the first checkup of the trial; time from surgery – the time from the last surgery required to treat chronic ear disease to the first checkup of the trial. PVRP: platelet- and extracellular vesicle-rich plasma; n: number of patients; M: average value; independent samples t-test; *Fisher’s exact test; Mdn: median value; **Mann–Whitney U-test; COMQ-12: chronic otitis media questionnaire 12; p-value < 0.05 denotes statistically significant difference. Coagulopathy occurred as a consequence of regular acetylsalicylic acid intake.