TABLE 1.
PVRP group (n = 11) | Control group (n = 11) | p | |
Gender | |||
Male (n, %) | 9 (82%) | 9 (82%) | 1.000 |
Female (n, %) | 2 (18%) | 2 (18%) | |
Age | |||
M ± SD (years) | 47 ± 18 | 52 ± 24 | 0.632‡ |
Comorbidities | |||
Yes (n, %) | 6 (55%) | 6 (55%) | 1.000 |
No (n, %) | 5 (45%) | 5 (45%) | |
Regular medicine intake | |||
Yes (n, %) | 3 (27%) | 6 (55%) | 0.387* |
No (n, %) | 8 (73%) | 5 (45%) | |
Allergies | |||
Yes (n, %) | 5 (45%) | 4 (36%) | 1.000* |
No (n, %) | 6 (55%) | 7 (64%) | |
Coagulopathy | |||
Yes (n, %) | 2 (18%) | 1 (9%) | 1.000* |
No (n, %) | 9 (82%) | 10 (91%) | |
Smoking | |||
Yes (n, %) | 2 (18%) | 5 (45%) | 0.361* |
No (n, %) | 9 (82%) | 6 (55%) | |
Alcohol consumption | |||
Yes (n, %) | 10 (91%) | 7 (64%) | 0.311* |
No (n, %) | 1 (9%) | 4 (36%) | |
Time to treatment | |||
Mdn (day–years) | 2,688–7.4 | 3,172–8.7 | 0.116** |
Time from surgery | |||
Mdn (days–years) | 4,644–12.7 | 5,224–14.3 | 0.573** |
COMQ-12 score | |||
Mdn | 33 | 34 | 0.977** |
Time to treatment – the time from the beginning of the problems due to chronic postoperative temporal bone cavity inflammation to the first checkup of the trial; time from surgery – the time from the last surgery required to treat chronic ear disease to the first checkup of the trial. PVRP: platelet- and extracellular vesicle-rich plasma; n: number of patients; M: average value; ‡independent samples t-test; *Fisher’s exact test; Mdn: median value; **Mann–Whitney U-test; COMQ-12: chronic otitis media questionnaire 12; p-value < 0.05 denotes statistically significant difference. Coagulopathy occurred as a consequence of regular acetylsalicylic acid intake.