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. 2021 Jul 21;16(7):e0254001. doi: 10.1371/journal.pone.0254001

Table 3. For every category, we applied lasso regression to predict the percentage of voters in the county that voted for Donald Trump or Hillary Clinton, and the Republican margin shift.

Prediction Variable Category Rank in category Overall coefficient
Rep. margin change `Malignant skin melanoma` Cancers 1 0.02653
Rep. margin change `Colon & rectum cancer` Cancers 2 0.02544
Rep. margin change `Lip & oral cavity cancer` Cancers 3 0.01959
Rep. margin change `Tracheal, bronchus, & lung ` Cancers 4 0.01902
Rep. margin change `Multiple myeloma` Cancers 5 0.01751
Rep. margin change `Rheumatic heart disease` Cardiovascular diseases 1 0.02951
Rep. margin change `Aortic aneurysm` Cardiovascular diseases 2 0.02736
Rep. margin change `Ischemic heart disease` Cardiovascular diseases 3 0.01447
Rep. margin change `Ischemic stroke` Cardiovascular diseases 4 0.01022
Rep. margin change Endocarditis Cardiovascular diseases 5 0.00712
Rep. margin change `% Screened` Clinical Care 1 0.01589
Rep. margin change `PCP Rate` Clinical Care 2 0.01524
Rep. margin change `Preventable Hosp. Rate` Clinical Care 3 0.00636
Rep. margin change `% With Access` Clinical Care 4 0.00426
Rep. margin change `% Vaccinated` Clinical Care 5 0.00341
Rep. margin change `Self-harm` Deaths of Despair 1 0.02214
Rep. margin change `Alcohol use disorders` Deaths of Despair 2 0.01750
Rep. margin change `Drug use disorders` Deaths of Despair 3 0.00257
Rep. margin change `Interpersonal violence` Deaths of Despair 4 0.00142
Rep. margin change `% Food Insecure` Health Behaviors 1 0.03853
Rep. margin change `% Smokers` Health Behaviors 2 0.03674
Rep. margin change `% Excessive Drinking` Health Behaviors 3 0.03035
Rep. margin change `Food Environment Index` Health Behaviors 4 0.01850
Rep. margin change opioid_prescribing_rate Health Behaviors 5 0.01282
Rep. margin change Meningitis Infectious diseases 1 0.03231
Rep. margin change Hepatitis Infectious diseases 2 0.02039
Rep. margin change `Diarrheal diseases` Infectious diseases 3 0.01853
Rep. margin change `HIV AIDS` Infectious diseases 4 0.01534
Rep. margin change `Lower respiratory infections` Infectious diseases 5 0.00370
Rep. margin change `Mortality risk, age 45–65` Life expectancy, YLL, and Mortality 1 0.03939
Rep. margin change `Mortality risk, age 25–45` Life expectancy, YLL, and Mortality 2 0.03855
Rep. margin change `Years of Potential Life Lost Rate` Life expectancy, YLL, and Mortality 3 0.01646
Rep. margin change `Mortality risk, age 0–5` Life expectancy, YLL, and Mortality 4 0.01298
Rep. margin change `Age-Adjusted Mortality` Life expectancy, YLL, and Mortality 5 0.01292
Rep. margin change `Other pneumoconiosis` Respiratory diseases 1 0.02393
Rep. margin change Asthma Respiratory diseases 2 0.01047
Rep. margin change `Other chronic respiratory ` Respiratory diseases 3 0.00917
Rep. margin change Asbestosis Respiratory diseases 4 0.00529
Rep. margin change `Interstitial lung disease` Respiratory diseases 5 0.00407
Rep. margin change `% Single-Parent Households` Social, Physical and Economic Environment 1 0.05328
Rep. margin change `Firearm Fatalities Rate` Social, Physical and Economic Environment 2 0.03071
Rep. margin change `% Children in Poverty` Social, Physical and Economic Environment 3 0.01253
Rep. margin change `Injury Death Rate` Social, Physical and Economic Environment 4 0.00925
Rep. margin change `% Homeowners` Social, Physical and Economic Environment 5 0.00901
% Trump 2016 `Acute lymphoid leukemia` Cancers 1 0.03711
% Trump 2016 `Liver cancer` Cancers 2 0.02191
% Trump 2016 `Other pharynx cancer` Cancers 3 0.01915
% Trump 2016 `Nasopharynx cancer` Cancers 4 0.01814
% Trump 2016 `Kidney cancer` Cancers 5 0.01802
% Trump 2016 `Other cardiovascular` Cardiovascular diseases 1 0.01340
% Trump 2016 `Ischemic heart disease` Cardiovascular diseases 2 0.01295
% Trump 2016 `Rheumatic heart disease` Cardiovascular diseases 3 0.01012
% Trump 2016 `Aortic aneurysm` Cardiovascular diseases 4 0.00909
% Trump 2016 `Ischemic stroke` Cardiovascular diseases 5 0.00889
% Trump 2016 `% Screened` Clinical Care 1 0.02656
% Trump 2016 `MHP Rate` Clinical Care 2 0.02017
% Trump 2016 `% Vaccinated` Clinical Care 3 0.01250
% Trump 2016 `% With Access` Clinical Care 4 0.00803
% Trump 2016 `PCP Rate` Clinical Care 5 0.00722
% Trump 2016 `Self-harm` Deaths of Despair 1 0.03750
% Trump 2016 `Alcohol use disorders` Deaths of Despair 2 0.03498
% Trump 2016 `Interpersonal violence` Deaths of Despair 3 0.02354
% Trump 2016 `Drug use disorders` Deaths of Despair 4 0.00690
% Trump 2016 physical_inactivity_crude Health Behaviors 1 0.03454
% Trump 2016 `% Food Insecure` Health Behaviors 2 0.02989
% Trump 2016 `MV Mortality Rate` Health Behaviors 3 0.02536
% Trump 2016 `Food Environment Index` Health Behaviors 4 0.02194
% Trump 2016 `Teen Birth Rate` Health Behaviors 5 0.02165
% Trump 2016 Hepatitis Infectious diseases 1 0.03141
% Trump 2016 `Diarrheal diseases` Infectious diseases 2 0.02719
% Trump 2016 `HIV AIDS` Infectious diseases 3 0.02079
% Trump 2016 `Lower respiratory infections` Infectious diseases 4 0.01920
% Trump 2016 Meningitis Infectious diseases 5 0.00957
% Trump 2016 `Years of Potential Life Lost Rate` Life expectancy, YLL, and Mortality 1 0.09069
% Trump 2016 `Mortality risk, age 5–25` Life expectancy, YLL, and Mortality 2 0.07097
% Trump 2016 `YPLL Rate (White)` Life expectancy, YLL, and Mortality 3 0.04372
% Trump 2016 `Mortality risk, age 0–5` Life expectancy, YLL, and Mortality 4 0.02479
% Trump 2016 `Mortality risk, age 65–85` Life expectancy, YLL, and Mortality 5 0.02457
% Trump 2016 `Chronic obstructive pulmonary ` Respiratory diseases 1 0.04661
% Trump 2016 `Interstitial lung disease` Respiratory diseases 2 0.01623
% Trump 2016 Asthma Respiratory diseases 3 0.01243
% Trump 2016 `Other pneumoconiosis` Respiratory diseases 4 0.00720
% Trump 2016 `Other chronic respiratory ` Respiratory diseases 5 0.00712
% Trump 2016 `% Single-Parent Households` Social, Physical and Economic Environment 1 0.06653
% Trump 2016 `% Severe Housing Problems` Social, Physical and Economic Environment 2 0.03953
% Trump 2016 `Firearm Fatalities Rate` Social, Physical and Economic Environment 3 0.03877
% Trump 2016 `% Homeowners` Social, Physical and Economic Environment 4 0.01254
% Trump 2016 `% Children in Poverty` Social, Physical and Economic Environment 5 0.01000

This table reports the variable importance for the top variables in each category.