Figure 2 .

Summary of the prediction algorithm. The query protein is introduced in FASTA format and evaluated with multiple prediction tools. Based on the respective outputs, the values of 14 numerical and Boolean variables are calculated. If certain conditions or thresholds are met, then specific TAGs plus additional information will be assigned to the query protein. Lastly, a check of the different assigned TAGs is performed in order to remove redundant information. If certain TAGs are in conflict, ‘Unknown’ is returned as a result. ^*, For the sake of clarity, particular details have been documented in Supplementary Table 3.