Table 2:
Patient characteristics
| Characteristic | Mutation Carriers, N = 1381 | Non-Mutation Carriers, N = 6131 | Overall, N = 751 | p-value2 |
|---|---|---|---|---|
| Sex | 0.65 | |||
| Female | 67 (49%) | 282 (46%) | 349 (46%) | |
| Male | 71 (51%) | 331 (54%) | 402 (54%) | |
| Age at diagnosis (years) | 7.4 ± 6.8 (0.0–19.0) | 8.4 ± 6.3 (0.0–19.0) | 8.2 ± 6.4 (0.0–19.0) | 0.11 |
| Multiple diagnoses | 0.0001519 | |||
| No | 124 (90%) | 595 (97%) | 719 (96%) | |
| Yes | 14 (10%) | 18 (3%) | 32 (4%) | |
| Deceased | ||||
| No | 117 (85%) | 519 (85%) | 636 (85%) | |
| Yes | 21 (15%) | 94 (15%) | 115 (15%) | |
1
Statistics presented: n (%); mean ± SD (minimum-maximum)
2
Statistical tests performed: chi-square test of independence and t-test, all two-sided