Table 1.
Kinases differentially regulated by cAMP localization
| Uniprot ID | Gene | Description | Modified residue | Endo (±SD) | PM (±SD) |
|---|---|---|---|---|---|
| P04049 | Raf1 | RAF proto-oncogene Ser/Thr-protein kinase; a regulatory link between the Ras GTPases and the MAPK/ERK cascade in determining cell fate decisions including proliferation, differentiation, apoptosis, survival, and oncogenic transformation. | Ser43 | 2.11 ± 0.06 | 1.60 ± 0.11 |
| Q00536 | Cdk16 | Cyclin-dependent kinase 16; plays a role in vesicle-mediated transport processes and exocytosis. | Ser153 | 2.51 ± 0.03 | 1.79 ± 0.15 |
| Q9BZ23 | Pank2 | Pantothenate kinase 2, master regulator of the CoA biosynthesis. | Ser189 | 1.51 ± 0.15 | 0.74 ± 0.01 |
| Q7KZI7 | Mark2 | Ser/Thr-protein kinase MARK2; regulates cell polarity and microtubule dynamics. | Ser619 | −1.35 ± 0.04 | −0.47 ± 0.19 |