Table 3.
Expression trends of filamins in various cancers
| Cancer Type | Filamin A |
Filamin B |
||||
|---|---|---|---|---|---|---|
| Protein Cell Lines | Protein Human Tissue | mRNA Human Tissue | Protein Cell Lines | Protein Human Tissue | mRNA Human Tissue | |
| Acute myeloid leukemia | ||||||
| Bladder | Increased (136) | |||||
| Breast | Increased (137, 138) | Increased (137) | Increased (136) | |||
| Cervical | Increased (139, 140) | |||||
| Colorectal | Increased (138, 141); Unfavorable prog. indicator (49) | Decreased (136) | ||||
| Endometrial | ||||||
| Esophageal | Increased (136) | |||||
| Gastric | Decreased (142) | Decreased (136) | ||||
| Glioma | Increased (143) | |||||
| Head and neck,including tongue and larynx | Increased (136) | |||||
| Liver | Increased (138) | |||||
| Lung | Increased (138, 144) | |||||
| Melanoma | Decreased (136) | |||||
| Neuroblastomas | ||||||
| Ovarian | Increased (138) | Increased (136) Decreased (136) | ||||
| Pancreatic | Increased (138) | Increased (4) Unfavorable Prog Indicator (49) | Increased (136) | |||
| Prostate | Increased (138, 145) | |||||
| Renal | Unfavorable prog. indicator (49) | Favorable prog. indicator (49) | ||||
| Thyroid | ||||||
| Salivary gland | ||||||
| Squamous cell carcinoma | Increased (136) | |||||
| Stomach | ||||||
| Urothelial | Unfavorable prog. indicator (49) | |||||
Prog., prognosis.