Table 1.
Tabular Representation showing the output of X3-DNA-DSSR in context of structural difference in both RNA sequences. Wild-type RNA sequence have changed in number of base pairs, bulges, internal loops, and atom based capping function compare to mutant. Change in above mentioned parameters induce a change in folding of SL1, SL2, and SL3 (shown in Fig. 1).
| Parameters | Wild-type | Mutant (C241T) |
|---|---|---|
| Total number of nucleotides | 300 | 300 |
| Total number of base pairs | 107 | 109 |
| Total number of multiplets | 8 | 8 |
| Total number of helices | 8 | 7 |
| Total number of stems | 17 | 17 |
| Total number of G-U Wobble pairs | 7 | 8 |
| Total number of atom-base capping interaction | 9 | 10 |
| Total number of splayed-apart dinucleotide | 33 | 33 |
| Consolidated into units | 15 | 15 |
| Total number of hairpin loops | 7 | 7 |
| Total number of bulges | 3 | 5 |
| Total number of internal loops | 6 | 5 |
| Total number of junctions | 1 | 1 |
| Total number of non-loop single-stranded segments | 6 | 6 |
| Total number of extended A-minor (type X) motifs | 3 | 3 |