Use of lipid-lowering drugs in NSTE-ACS patients after discharge - Summary of recommendations and evidence | ||
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In patients with a previous ACS diagnosis, LDL-c should be reduced to < 50 mg/dL, and HDL-c should be reduced to < 80 mg/dL. | I | B |
When tolerated, preference should be given to high-intensity statins. | I | A |
When the LDL-c target is not achieved with statins at the maximum tolerated dose, ezetimibe should be added. | I | A |
PCSK9 inhibitors can be considered in patients who are receiving statin treatment at the highest tolerated dose, associated or not with ezetimibe, and who have not reached recommended LDL-c or HDL-c target levels. | IIa | A |